Bus from Saint Paul to Des Moines
Book your bus ticket to Des Moines from Saint Paul today
Duration 4 hours 50 minutes (fastest time)
Departures Up to 1 service per day
Why travel with Megabus?
Multiple Stops, One Transaction
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Saint Paul to Des Moines bus details
Our route JL01 bus stops at 7 stops between Saint Paul and Des Moines. The bus sets off from Jefferson Lines bus stop at St. Paul (Union Depot) - 240 Kellogg Blvd. E. and drops you off at Burlington Trailways Bus Stop at Des Moines - 1641 E. Euclid
Saint Paul
Des Moines

Our Network
We serve 500+ North American cities through partner operated routes. When you buy bus tickets with Megabus, we offer options to take you from your point of origin to your final destination in one transaction across multiple partners (if needed).
Frequently Asked Questions
How long does it take to travel from Saint Paul to Des Moines by bus?
The fastest bus from Saint Paul to Des Moines takes 4 hours 50 minutes
When is the first bus from Saint Paul to Des Moines?
The earliest bus from Saint Paul to Des Moines leaves at 11:15 PM
When is the last bus from Saint Paul to Des Moines?
The latest bus from Saint Paul to Des Moines leaves at 11:15 PM
How many daily bus trips are there from Saint Paul to Des Moines?
megabus runs up to 1 trips per day from Saint Paul to Des Moines. View our departure schedule and book your trip
How can I pay for my Saint Paul to Des Moines bus ticket?
megabus offers a wide range of payment methods for our tickets, including major credit card providers and Google pay.
Where is the Saint Paul megabus bus stop?
The bus sets off from Jefferson Lines bus stop at St. Paul (Union Depot) - 240 Kellogg Blvd. E.
Where is the Des Moines megabus bus stop?
The bus drops you off at Burlington Trailways Bus Stop at Des Moines - 1641 E. Euclid
Can I track my Saint Paul to Des Moines bus ?
megabus offers real-time bus tracking on our website, so you check your bus location by service number or route. No getting caught off guard with delays here!